Solifenacin Manufacturers / Suppliers
Somu Organo-Chem Pvt.
Ltd is also known for Solifenacin Manufacturers and Suppliers in Bangalore,
Karnataka. Solifenacin is used as a medicine to treat contraction of overactive
bladder.
Somu Organo-Chem Pvt.
Ltd was established in the year 1995 with a manufacturing unit at Malur near
Bangalore to manufacture Speciality Fine Chemicals, Pharma Intermediates,
Perfumery and flavour Intermediates, Agro Chemical Intermediates, Mining
Chemicals and Flotation Reagents.
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| Solifenacin Manufacturers / Suppliers |
Solifenacin, marketed
as solifenacin succinate under the trade name Vesicare, is a urinary
antispasmodic of the anticholinergic class. It is used in the treatment of
overactive bladder with urge incontinence.
Solifenacin is
contraindicated for people with urinary retention, gastric retention, uncontrolled
or poorly controlled closed-angle glaucoma, severe liver disease.
Side effects
The most common side
effects of solifenacin are dry mouth, blurred vision, and constipation. As all
anticholinergics, solifenacin may rarely cause hyperthermia due to decreased
perspiration.
Solifenacin is
metabolized in the liver by the cytochrome P450 enzyme CYP3A4. When
administered concomitantly with drugs that inhibit CYP3A4, such as
ketoconazole, the metabolism of solifenacin is impaired, leading to an increase
in its concentration in the body and a reduction in its excretion.
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| Solifenacin Manufacturers / Suppliers |
Mechanism of action
Solifenacin is a
competitive cholinergic receptor antagonist, selective for the M3
receptor subtype. The binding of acetylcholine to these receptors, particularly
M3, plays a critical role in the contraction of smooth muscle. By
preventing the binding of acetylcholine to these receptors, solifenacin reduces
smooth muscle tone in the bladder, allowing the bladder to retain larger
volumes of urine and reducing the number of micturition, urgency and
incontinence episodes. Because of a long elimination half life, a once-a-day
dose can offer 24-hour control of the urinary bladder smooth muscle tone.
Our Commitment
We Endeavour to be
the best company to 'work for' and the best company to 'buy from'. We will do
this through
- Surpassing customers expectations by providing prompt, efficient and better services,
- Building and Maintaining Customer Relationships.
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| Solifenacin Manufacturers / Suppliers |
Our Mission
- · To strive relentlessly and constantly improve ourselves, our team, our products and our services so as to become the best.
- · To expand our product line and ensure supply of complaint -free products. To achieve customer satisfaction through continuous improvement.
For more details: Solifenacin Manufacturers / Suppliers
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